<?xml version="1.0" encoding="UTF-8"?><xml><records><record><source-app name="Biblio" version="7.x">Drupal-Biblio</source-app><ref-type>17</ref-type><contributors><authors><author><style face="normal" font="default" size="100%">Daniel B. COELHO</style></author><author><style face="normal" font="default" size="100%">Eduardo M. PIMENTA</style></author><author><style face="normal" font="default" size="100%">Rosse, Izinara C</style></author><author><style face="normal" font="default" size="100%">Veneroso, Christiano</style></author><author><style face="normal" font="default" size="100%">et. al.</style></author></authors></contributors><titles><title><style face="normal" font="default" size="100%">Alpha-Actinin-3 R577X Polymorphism Influences Muscle Damage and Hormonal Responses After a Soccer Game</style></title><secondary-title><style face="normal" font="default" size="100%">JOURNAL OF STRENGTH AND CONDITIONING RESEARCH</style></secondary-title></titles><dates><year><style  face="normal" font="default" size="100%">2019</style></year></dates><urls><web-urls><url><style face="normal" font="default" size="100%">https://journals.lww.com/nsca-jscr/Abstract/2019/10000/Alpha_Actinin_3_R577X_Polymorphism_Influences.10.aspx</style></url></web-urls></urls><volume><style face="normal" font="default" size="100%">33</style></volume><pages><style face="normal" font="default" size="100%">2655-2664</style></pages><language><style face="normal" font="default" size="100%">eng</style></language><abstract><style face="normal" font="default" size="100%">&lt;p style=&quot;text-align: justify;&quot;&gt;
	The purpose of this study was to evaluate indicators of muscle damage and hormonal responses after soccer matches and its relation to alpha-actinin-3 (ACTN3) gene expression (XX vs. RR/RX), considering that the R allele produces alpha-actinin-3 and provides greater muscle strength and power. Thirty players (10 XX and 20 RR/RX) younger than 16 years were evaluated in this study. Blood samples were collected immediately before, after, 2, and 4 hours after the games to assess muscle damage (creatine kinase [CK] and alpha-actin) and hormonal responses (interleukin-6 [IL-6], cortisol, and testosterone). Postgame CK was higher as compared to the pregame values in both groups and it was also higher in the RR/RX (&lt;em xmlns:mrws=&quot;http://webservices.ovid.com/mrws/1.0&quot;&gt;p&lt;/em&gt;&amp;nbsp;&amp;lt; 0.05) than in the XX. The concentrations of alpha-actin and IL-6 were similar for both groups and did not change over time. Testosterone was increased after the game only in the RR/RX group (&lt;em xmlns:mrws=&quot;http://webservices.ovid.com/mrws/1.0&quot;&gt;p&lt;/em&gt;&amp;nbsp;&amp;lt; 0.05). Cortisol concentrations in group RR/RX were higher immediately after the game than before the game, and 2 and 4 hours after the game the concentration decreased (&lt;em xmlns:mrws=&quot;http://webservices.ovid.com/mrws/1.0&quot;&gt;p&lt;/em&gt;&amp;nbsp;&amp;lt; 0.05). The RR and RX individuals presented higher markers of muscle microtrauma and hormonal stress, probably because they performed more speed and power actions during the game, which is a self-regulated activity. From the different responses presented by RR/RX and XX genotypes, we conclude that the genotypic profile should be taken into account when planning training workloads and recovery of athletes.
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</style></abstract><issue><style face="normal" font="default" size="100%">10</style></issue></record></records></xml>